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SB 742457

CAS No. 607742-69-8

SB 742457 ( GSK742457 )

Catalog No. M15279 CAS No. 607742-69-8

SB742457 is a highly selective 5-HT6 receptor antagonist with pKi of 9.63.

Purity : >98%(HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
5MG	61	In Stock
10MG	98	In Stock
25MG	200	In Stock
50MG	320	In Stock
100MG	507	In Stock
500MG	1062	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

SB 742457
Note

Research use only, not for human use.
Brief Description

SB742457 is a highly selective 5-HT6 receptor antagonist with pKi of 9.63.
Description

SB742457 is a highly selective 5-HT6 receptor antagonist with pKi of 9.63, exhibits >100-fold selectivity over other receptors. Phase 2.
Synonyms

GSK742457
Pathway

Endocrinology/Hormones
Target

5-HT Receptor
Recptor

5-HT6
Research Area

Neurological Disease
Indication

——

Chemical Information

CAS Number

607742-69-8
Formula Weight

353.44
Molecular Formula

C19H19N3O2S
Purity

>98%(HPLC)
Solubility

Ethanol: 2 mg/mL (5.65 mM); DMSO: 78 mg/mL (220.68 mM)
SMILES

O=S(C1=CC2=CC=CC(N3CCNCC3)=C2N=C1)(C4=CC=CC=C4)=O
Chemical Name

3-Phenylsulfonyl-8-(piperazin-1-yl)quinoline

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Chuang ATT, et al. Alzheimers Dement, 2006, 2, S631–S632 (abstract).

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